Preparation of bismuth nano oxide-zeolite composite and evaluation of its catalytic activity in the Biginelli reaction
کد مقاله : 1127-INZC6
شهرزاد معرفت ایزدی *1، مهسا صالحی2، معصومه خاتمیان3، زرین قاسمی2
1دانشکده شیمی
2دانشگاه تبریز دانشکده شیمی
3شیمی معدنی - دانشگاه تبریز
چکیده مقاله:
Zeolites as microporous materials can be used as catalyst. In this research, Nano bismuth oxide-zeolite composite was prepared by SSD method.The composite was examined by Fourier transform infrared spectroscopy(FT-IR), X-ray diffraction (XRD) and Scanning electron microscopy (SEM). The catalytic performance of nano bismuth oxide-zeolite composite was evaluated by its utilization in biginelli reaction.
The prepared composite catalyzed Biginelli reaction for the synthesis of 3,4-dihydropyrimidin-2(1H) derivatives in high yields under solvent-free condition by the reaction of aldehyde, β-diketoester and urea. The product was identified by measuring its melting point and using FT-IR and NMR techniques. Acid catalyzed Biginelli reaction is a versatile route for the synthesis of dihydroprimidinones. DHPMs and their derivatives have been receiving considerable attention, because they exhibit a wide of biological and pharmacological properties such as antiviral, antibacterial, antitumor, anticancer, antihypertensive and most importantly, as calcium channel modulators. The great potential of DHPMs in pharmaceutical fields has accordingly triggered growing interest in their synthetic study.
کلیدواژه ها:
Nano bismuth oxide-zeolite, Solid state dispersion, Biginelli reaction
وضعیت : مقاله پذیرفته شده است